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The short answer is: Adobe Illustrator. Adobe Creative Cloud is the industry standard and if you look at any graphic design job description, they’re going to expect you to have experience with Adobe Creative Cloud, specifically Illustrator, InDesign, and Photoshop.
My very first design job was in college for a state government agency. I had taken exactly one class on Adobe Illustrator and one on basic graphic design principles with InDesign. I still don’t know how I was the one chosen for that position. Unless I was the only one who applied, which may have been the case, thinking back on it…